# Biomat S.r.l. — Coated Microplates & IVD Surfaces (Ala, Trento, Italy)
> Italian manufacturer of coated 96-well microplates, PCR products, ELISA reagents and custom surface-modification services for in vitro diagnostics (IVD) and life-science research. Over 30 years of expertise in surface engineering. ISO 9001:2015 certified.

Last updated: July 2026

A clean Markdown version of every page listed below is available: append .md to the page URL (for example https://www.biomat.it/surfaces/carboxylated-surfaces.md). The .md link is given explicitly on each entry. Homepage Markdown: https://www.biomat.it/index.md · Full extended text: https://www.biomat.it/llms-full.txt

## Company
- Founded: 1992
- Headquarters: Via Trento 124, 38061 Ala, fraz. S. Margherita (TN), Italy
- VAT: IT02144590227
- Quality: ISO 9001:2015 certified; Certificate of Quality released for every lot
- Core competence: surface modification, microplate engineering, coating services, custom/OEM development
- Markets: worldwide (primary: USA, Germany, UK, France, Italy)
- Languages: English, Italian
- Contact: info@biomat.it | +39 0464 357951
- Website: https://www.biomat.it

## Products — 96-Well Plates (by binding surface)
- [High Binding 96-Well Plates](https://www.biomat.it/product/microplates/96-well-plates/high-binding-96-well-plates/): hydrophilic surface, ~400–500 ng IgG/cm², for ELISA, CLIA, FIA, LIA. Clear/white/black; breakable strip, strip, solid. Markdown: https://www.biomat.it/product/microplates/96-well-plates/high-binding-96-well-plates.md
- [Medium Binding 96-Well Plates](https://www.biomat.it/product/microplates/96-well-plates/medium-binding-96-well-plates/): hydrophobic polystyrene, ~100–200 ng IgG/cm², for hydrophobic biomolecules. Markdown: https://www.biomat.it/product/microplates/96-well-plates/medium-binding-96-well-plates.md
- [No Binding 96-Well Plates](https://www.biomat.it/product/microplates/96-well-plates/no-binding-96-well-plates/): treated to prevent biomolecule adsorption.
- [Streptavidin Plates](https://www.biomat.it/product/microplates/96-well-plates/streptavidin-plates/): biotinylated molecule capture, 12 pmol biotin/well. Markdown: https://www.biomat.it/product/microplates/96-well-plates/streptavidin-plates.md
- [High Binding Streptavidin Plates](https://www.biomat.it/product/microplates/96-well-plates/high-binding-streptavidin-plates/): polymeric streptavidin, > 35 pmol d-biotin/well, for biotinylated low molecular weight molecules. Markdown: https://www.biomat.it/product/microplates/96-well-plates/high-binding-streptavidin-plates.md
- [Carboxylated Plates](https://www.biomat.it/product/microplates/96-well-plates/carboxylated-plates/): COOH-activated, covalent coupling of amine-bearing molecules via EDC. Markdown: https://www.biomat.it/product/microplates/96-well-plates/carboxylated-plates.md
- [Amine Activated (Aminated) Plates](https://www.biomat.it/product/microplates/96-well-plates/amine-activated-96-well-plates/): primary amine surface, covalent coupling of carboxyl- or thiol-bearing molecules. Markdown: https://www.biomat.it/product/microplates/96-well-plates/amine-activated-96-well-plates.md
- [Goat Anti-Human IgG Plates](https://www.biomat.it/product/microplates/96-well-plates/goat-anti-human-igg-plates/): Fcγ-specific capture, 50 ng/well binding capacity, 0.1 ng/well sensitivity. Markdown: https://www.biomat.it/product/microplates/96-well-plates/goat-anti-human-igg-plates.md
- [Goat Anti-Human IgM Plates](https://www.biomat.it/product/microplates/96-well-plates/goat-anti-human-igm-plates/): Fcμ-specific capture.
- [Goat Anti-Human IgA Plates](https://www.biomat.it/product/microplates/96-well-plates/goat-anti-human-iga-plates/): Fcα-specific capture.
- Other coatings: Protein A / A-G / G, Biotin, Neutravidin, Poly-L-Lysine, Poly-L-Arginine, Maleimide, Concanavalin A, Jacalin, Wheat Germ, Anti-Mouse/Rabbit IgG, Heparin Catcher. Full list: https://www.biomat.it/our-products/microplates/96-well-plates/

## Surfaces — technical documentation
Surface pages describe the coating chemistry, binding mechanism, experimental binding data and application criteria, independently of the product format. They support the technical decision; the product pages above carry formats, prices and ordering.

- [Streptavidin Coated Surface](https://www.biomat.it/surfaces/streptavidin-coated-surfaces/): tetrameric streptavidin (60 kDa), universal biotin capture, 12 pmol biotin/well and 100 ng biotinylated HIgG/well, full stability dataset. Markdown: https://www.biomat.it/surfaces/streptavidin-coated-surfaces.md
- [Streptavidin High Binding Coated Surface](https://www.biomat.it/surfaces/streptavidin-high-binding-coated-surfaces/): polymer of 6–8 streptavidin molecules, > 35 pmol d-biotin/well, for biotinylated low molecular weight molecules and competitive assays. Markdown: https://www.biomat.it/surfaces/streptavidin-high-binding-coated-surfaces.md
- [Anti-Human IgG/IgM/IgA Coated Surfaces](https://www.biomat.it/surfaces/anti-human-igg-igm-iga/): affinity-purified goat antibodies, Fc-specific capture of human immunoglobulins (Fcγ, Fcμ, Fcα), full isotype range from one manufacturer, binding capacity and sensitivity per isotype. Markdown: https://www.biomat.it/surfaces/anti-human-igg-igm-iga.md
- [Carboxylated Surface](https://www.biomat.it/surfaces/carboxylated-surfaces/): COOH groups for covalent immobilization of amine-bearing compounds via EDC-mediated amination; for small peptides (MW 1,000–5,000 Da), drugs, toxins, hormones. Markdown: https://www.biomat.it/surfaces/carboxylated-surfaces.md
- [Aminated (primary amine) Surface](https://www.biomat.it/surfaces/aminated-surfaces/): NH2 groups for covalent immobilization via NHS, SMCC, EDC/Sulfo-NHS or glutaraldehyde crosslinkers; complementary to the carboxylated surface. Markdown: https://www.biomat.it/surfaces/aminated-surfaces.md
- Full surface range (Protein A / A-G / G, Biotin, Neutravidin, Maleimide, Concanavalin A, Jacalin, Wheat Germ, Poly-L-Lysine, Poly-L-Arginine, Heparin Catcher, Anti-Tag, Immunotoxicity, Mab Isotyping, Secondary Antibodies): https://www.biomat.it/surfaces/

### Covalent coupling: which surface to choose
- Molecule with a free amino group (NH2) → Carboxylated surface (amide bond via EDC)
- Molecule with a free carboxyl group (COOH) → Aminated surface (via EDC / Sulfo-NHS)
- Molecule with a free thiol group (SH) → Aminated surface via SMCC, or Maleimide surface
- Biotinylated molecule → Streptavidin surface (or Streptavidin High Binding for low MW targets)

## Products — Coated PCR strip tubes & plates
Coated PCR products combine the PCR format with a functionalised surface, enabling protocols that integrate amplification and capture in the same vessel. 8 connected 0.2 ml tubes in clear polypropylene, thin walls for heat transfer, flat caps, numerically identified tubes, pre-blocked with standard proteic blocking. Used in the development of an ultra-high-throughput SARS-CoV-2 population screening assay based on surface-based tagmentation.

- [Streptavidin Coated PCR 8 Strip Tubes](https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/streptavidin-coated-pcr-tubes/): ~5–6 pmol d-biotin/tube. Markdown: https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/streptavidin-coated-pcr-tubes.md
- [High Binding Streptavidin PCR 8 Strip Tubes](https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/high-binding-streptavidin-high-pcr-8-strip-tubes/): > 20 pmol d-biotin/tube. Markdown: https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/high-binding-streptavidin-high-pcr-8-strip-tubes.md
- [Carboxylated PCR 8 Strip Tubes](https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/carboxylated-pcr-8-strip-tubes/)
- [Protein A/G PCR 8 Strip Tubes](https://www.biomat.it/product/pcr-products/coated-pcr-strip-tubes/protein-a-g-pcr-8-strip-tubes/)
- [Coated PCR Plates](https://www.biomat.it/our-products/pcr-products/coated-pcr-plates/): streptavidin, streptavidin high binding, carboxylated.
- [Full PCR range](https://www.biomat.it/our-products/pcr-products/)

## Products — Other categories
- [ELISA Reagents](https://www.biomat.it/our-products/reagents-for-elisa/): coating buffer, blocking solution, wash buffer, diluent/stabilizer, TMB & stop solution, starter kit.
- [Other Microplates](https://www.biomat.it/our-products/microplates/): cell & tissue culture treated, HTS, glass-bottom, KingFisher™ consumables.
- [Special Products](https://www.biomat.it/our-products/special-products/): anti-tag plates, immunotoxicity plates, mouse monoclonal antibody isotyping plates.
- [Accessories for IVD](https://www.biomat.it/our-products/accessories-for-ivd/): desiccant, barrier bags, holding frames.

## Services — custom development and OEM manufacturing
Biomat is a manufacturer, not a distributor: coating, engineering and production are in-house. Custom and OEM development is available for IVD kit manufacturers and reagent companies that need surfaces, formats or devices not available from catalogue.

- [Custom Product Development (OEM)](https://www.biomat.it/services/custom-microplates/): bespoke coated microplates and devices for IVD kit manufacturers. Custom well geometries, surface chemistries, formats, colors, barcoding and packaging. Process: requirements definition, design & 3D prototyping, material & surface selection, collaborative testing, ISO-certified production. Contact Biomat for coating options, minimum order quantities and turnaround, which are defined per project. Markdown: https://www.biomat.it/services/custom-microplates.md
- [Coating Services & Surface Treatment](https://www.biomat.it/services/coating-services/): chemical modification, biological coating and plasma treatment applied to the customer's own devices (polystyrene, polypropylene, COC, POC). Technology transfer from lab protocol to industrial scale. Markdown: https://www.biomat.it/services/coating-services.md
- [Engineering Services](https://www.biomat.it/services/engineering/): product design, 3D prototyping, tooling design, moulding through to packaged and labelled product. In-house since 1992. Markdown: https://www.biomat.it/services/engineering.md
- [Plasma Surface Treatment](https://www.biomat.it/services/plasma-treatments/): glow-discharge plasma applied to microplates and IVD plastics: cleaning, activation, grafting, deposition. Not a cosmetic or medical plasma procedure, and not related to blood plasma. Markdown: https://www.biomat.it/services/plasma-treatments.md

## Applications & Technical Guides
- [ELISA Assay: principle, types and plate selection](https://www.biomat.it/applications-techniques/elisa-assay/): how ELISA works; Direct, Indirect, Competitive, Sandwich formats; ELISA vs CLIA vs FIA; microplate selection. Markdown: https://www.biomat.it/applications-techniques/elisa-assay.md
- [Choosing the Right Microplate](https://www.biomat.it/applications-techniques/choosing-microplate-for-assay/): materials, surface chemistry, biomolecule-to-plate mapping, formats, colors, common errors.
- [Medium vs High Binding Well Plates](https://www.biomat.it/applications-techniques/medium-and-high-binding-well-plates/): Biomat's own adsorption test data on BSA, human IgG and poly-DL-alanine; how amino acid composition drives surface choice. Markdown: https://www.biomat.it/applications-techniques/medium-and-high-binding-well-plates.md
- [Plates for Immunotoxicity ELISA tests](https://www.biomat.it/applications-techniques/coated-plates-for-immunotoxicity-elisa-test/)
- [Mouse Monoclonal Antibody Isotyping Microplates](https://www.biomat.it/applications-techniques/mouse-monoclonal-antibody-isotyping-coated-microplates/)
- [ELISA Plates for Coronavirus COVID-19](https://www.biomat.it/applications-techniques/coronavirus-covid-19-elisa-plates/)
- [Biotin Binding Surfaces](https://www.biomat.it/applications-techniques/biotin-binding-surfaces/)

## Key technical facts
- High binding vs medium binding: high binding plates have a mixed hydrophobic/hydrophilic surface (chemical modification) for stronger adsorption of hydrophilic biomolecules; medium binding plates are purely hydrophobic polystyrene, better for hydrophobic molecules.
- Binding capacity, high binding: ~400–500 ng IgG/cm². Medium binding: ~100–200 ng IgG/cm².
- Binding capacity, streptavidin: 12 pmol biotin/well (200 µl), 100 ng biotinylated HIgG/well. Streptavidin high binding: > 35 pmol d-biotin/well.
- Binding capacity, anti-human surfaces: IgG 50 ng/well (sensitivity 0.1 ng/well); IgM ≤ 300 ng/well (sensitivity 10 ng/ml); IgA ≤ 100 ng/well (sensitivity 0.700 ng/ml).
- Covalent coupling: carboxylated surface binds amine-bearing molecules via EDC; aminated surface binds carboxyl- or thiol-bearing molecules via NHS/SMCC/EDC/glutaraldehyde. Both immobilise small peptides (MW 1,000–5,000 Da), drugs, toxins and hormones that adsorb weakly or not at all.
- Formats: breakable strip, strip, solid. Colors: clear (absorbance), white (luminescence), black (fluorescence).
- Standards: SBS-compliant footprint, automation-compatible, CV < 5% (CV < 10% on anti-human surfaces), shelf life up to 5 years.
- Streptavidin coating stability: verified over 30 months in a non-air-conditioned warehouse (10–40°C), under transport temperature stress and under strong chemical contacts (SDS, formamide, NaOH, urea 8M).
- Use: For Research Use Only.

## Company & trust
- [About Biomat](https://www.biomat.it/about-biomat/)
- [Why work with Biomat](https://www.biomat.it/why-work-with-biomat/)
- [Quality & Certifications](https://www.biomat.it/quality/): ISO 9001 certified since 2002, updated to ISO 9001:2015 in June 2017. Every lot tested for uniformity and reproducibility, compared against previous lots including aging stages.
- [Scientific Citations](https://www.biomat.it/citations/): peer-reviewed publications using Biomat products.
- [Sustainability](https://www.biomat.it/about-biomat/sustainability/): facilities powered by 100% renewable energy.

## Contact
- Request a quote: https://www.biomat.it/request-quote/
- Contact: https://www.biomat.it/contact-us/
- Email: info@biomat.it · Phone: +39 0464 357951
- Address: Via Trento 124, 38061 Ala, fraz. S. Margherita (TN), Italy · VAT: IT02144590227