The Challenge of Coating and Surface Modification on New Devices and Polymers

The availability of new polymers with improved physical and optical properties and the use of new moulding and machining techniques, for more precise and micro-finished devices, besides offering a big potential, pose new challenges whenever the user needs to obtain particular properties.

As an example to transfer such a common property as the protein binding capacity from polystyrene (High Binding treated) to a different polymer with better physical properties (e.g. transparency), needs quite a lot of testing.

A basic knowledge of the properties of each material is needed, but, since nearly every application has its own specificity, the know-how of the companies which operate in this field must include:

  • The capability to transfer the technology to different applications,materials, etc.
  • The know-how for developing testing methods for evaluating the status of the surface: is the coating molecule active and are its binding sites available?

Therefore the supplier of coated or modified surfaces must give a product with demonstrated and demonstrable properties, so that the user can rely on a “safe” support for its product or technology.

Moreover , often the user is concentrated on its own tasks and he must not be expected to focus his energies to develop testing methods, so he needs to rely on the support of the supplier, where it is needed, to jointly develop the testing method.

Our experience, which includes the cooperation with primary scientific institutions, enables us to offer a reliable service for companies, laboratories, researchers and institutions operating in the diagnostic and pharmaceutical fields, for such applications as:

  • Immobilization of oligonucleotides on biocoated microplates
  • Poly-L-lysine coated microplate for Purified DNA binding
  • Streptavidin coating onto proprietary micro-fluidic devices made of different polymers
  • Activation and coating of POC devices
  • Cell binding on PE membrane

exploiting the currently available technologies for biotechnology.

Such areas as:

the development of new drugs
assays related to DNA

require a very specific knowledge and expertise.

Moreover transferring a method from the laboratory to the industrial application, can be time and money consuming, since, besides the expertise, it needs investments into equipments which could be used only for small pre-series.

Outsourcing is a response to these issues, where the supplier must offer: